RNA Details
Disease Name
pancreatitis
Tissue
pancreas
RNA Symbol
NOTCH-2
RNA ID
RNA Type
mRNA
Alteration Pattern
dysregulation
Species
homo sapiens
Detection Methods
qRT-PCR; immunohistochemistry
Target
NA
Pathway
NOTCH SIGNALING PATHWAY
PubMed ID
Title
Pancreatic regeneration in chronic pancreatitis requires activation of the notch signaling pathway
Year
2006
Function
"These findings suggest a possible role of the notch pathway during pancreatic regeneration since jagged-1 inhibits inducible collagen-1 production, suggesting a new mechanism of tissue repair in this disease."